European Stars And Stripes (Newspaper) - February 27, 1988, Darmstadt, Hesse Brian Barman getting a hug Iron his Mother above and playing Ullh is Bike right receives pioneering medical treatment Tor the rare gaucher s disease. Medical Poi by Daniel o. Haney associated press Rian German. Age 3. Was 33 India s Lall ind 25 inches around his belly was so swollen thai his Mother said he looked Ito a cabbage Wilh legs Brian was a loser in Hie Gunelic toll cry. I a game every person to be plays at Conception. Because to descends from Eastern european jews. The Odds were i in 676 Hal he would be born with an obscure illness Calion Gatscher s disease. Bui because his parents Bolh carried one recessive Gene for this disease the Odds word 1 in 4 Hal a would gel in. And he did like 15,000 to 20,000 Olfier americans he inherited iwo bad versions of a gone that helps overs to one of the body s arcane housekeeping choices cleaning upward Oul blood cells it another Way. However. He was unusually Lucky Brian happened o he pal enl at the Lodeal government s health research comp Lei in Bol Hes a myal just the or jul Mac ii researchers working Thuro Unrun or. Roscono o Brady had Boon trying Lor 30 years to Isol Alc purify and modify the enzyme that is body lacked Altos Covial false starts Hoy hoped they had hit Al East upon the ought formula on. Dec. 22,1983. Just thick weeks before he was scheduled to have his spleen Omo cd Brian received an injection of modified ii worked. Or soil appeared now at ago 7, Brian a Lull gets Iarj shots every thursday and he still shows some signs of the disease. His belly is a bit larger than Normal Bui to is clearly a Happy Bright energetic third grader. He 3 also a soil of medical Pioneer for he is the Only person to receive regi Lar therapy with what some a Perls believe will prove to to the Lisl Success Lyl treatment Tot gaucher s Desuas other researchers Are not so sus Clear. I decl us a Miracle " to Brady. Iho boy s Impero Voniel and the potential it May hold Lor orters Are Tho rewards of a career largely spent studying one rare disease ii cd Flinty is to says a look along Lime did lil this started in 1957, thirty years " the ordeal lorb an and his parents began in Ine Spring of l9b3when mrs Barman glanced Al her son while he was napping 1 i noticed that Brian s belly looked very big to me she remembers she had already brought this up with two other doctors who ass Tod hoi nothing was wrong. This Lime though she asked a surgeon who lived nearby to examine her boy. He said. There s a big mass in Sheie " his spleen was enlarged. Al Lisl doctors suspected leukaemia. But finally the diagnosis came Back Gaucho s disease i Iran locally racked my mrs. Keirnan said we had Aboul 10 minutes on it in medical school i could l remember what Al was Al she quickly Learned thai some of the world s spoils were Down the Load irom the family Home m Polacca my Al the National in Shulo of no urological and communicative disorders and . Where Brady is chief of the developmental and metabolic neurology Branco she approaches or John a Barranger then the clinical director to Bradys Ioup i asked him in he would Tot a work g alis i Odin l want Lobo paid. I wanted to Icahn i could about this d,seaso." she closed her family practice and Tagan seeing gaucher s patients she Learned that gaucher s disease is one of a handful of so alled Lipil storage disorders including Tay Sachs disease Are Roost common an Ong Ash Enart jews those who Craigi Ald from a Lorn Eui pc when blood eels Oul. Ine body recycles them by breaking Down then building materials Inelus no a tally substance called to do this it mates a specialized enzyme called however in gaucher s victims. Inc Gene Ilion makes this Enimo is delo Clive As a i suit Bunji up in their bodies 11 lends to Cloteel in cells called Macro Tiac in the Tver. Bonoma to and spleen the consequences vary Greally Horn Poison to Poison some Clio in child hush. Page h the stars and stripes
