European Stars And Stripes (Newspaper) - June 24, 1986, Darmstadt, Hesse                                Tuesday june 24, 1986 the stars and stripes of a p3ge cure for baldness there s the rub Washington a Hope Springs eternal but often hair does not so millions of balding men and thousands of Wall Street speculators ate anxiously awaiting word from the government on whether a Safe and Clicc Tive treatment for baldness finally his been found. The drug Ivy arc watching is Minoti Dif. Produced by the Upjohn co. Under the Brand name to Nilon it has been used for 21 years to treat severe High blood pressure because it opens Small blood a Cess is. Hut it had a curious Side effect. About 8 1 percent of people taking Mhz Vidu tablets grew hair on the forehead temples or upper Cheeks Iii ally later for some on the Back arms legs or Scalp because of the weird locations the hair growth was considered an annoyance at the h Usi to levied because the powerful potentially dangerous drug was used Only inpatients who did not respond to safer blood pressure drugs. Bui Upjohn scientists began to wonder what would happen if a solution of minoxidil was Nibbi d on a Bald Scalp. They tried and found Scalp hair. Upjohn Bym full Icale clinical testing of regain its Brand name for the topical solution in 1983. Last year the Michigan company filed an application asking the food and drug administration to approve minoxidil As a treatment or male pattern baldness. That appt ideation now is pending. But the course of the review process usually a Slaid and analytical procedure has been a circus since word of the drug spread. Based on Early research thousands of Bald men besieged their doctors for help and physicians responded with prescriptions for Lon itch and directions for pharmacist to crush the Small White pills to powder and dissolve them in solution. That kind of Bootleg Medicine is Legal Al though both Thesda and the company say they frown on the practice because of the potential risk of he untested procedure. On Wall Street speculators eyeing a potential mar Fields tilled again near chernobyl Moscow a work has started again on six farms near the chernobyl nuclear Power Plant but Farmers Are Al Lowed to till the land for just 10 Days before being replaced by other workers soviet newspaper said sunday. The English language in weekly mos cow news said in a Brief report that Field work has resumed on six farms i chernobyl District after being interrupted by the april 26 Accident that ripped open he no. 4 reactor at the chernobyl Power station releasing a Cloud of radiation eventually detected around the world. Echoing the tone of much recent soviet reporting on the chernobyl disaster the paper concluded that life with its summer tasks is resuming to Normal in the  there has been no word on when fever the bulk of More than 100,000 peo ple evacuated from areas of the Northern Ukraine and Southern byelorussian after the Accident will return to their Homes. Two Small villages in the 18-mile zone around the Plant that was evacuated have been reported declared Safe for reoccupation but other report have made Clear that extra housing is being built for some evacuees while still others have already left the Northern Ukraine to work in other parts of the Republic or other areas of the soviet Union. Act some estimate at 55 million an kans. Sent up John Stock soaring. It went from t.13 a share in Early 1985 to $ 174 a share on May 2, when it split 2-for-l, then to si03.75 on june 13. The Market s concern about possible Fra action was dramatically demonstrated last week when Thesda released a Tetter to Upjohn accusing the company of issuing a misleading press release about the drug. The fi5a Sud the release overstated the Cut Active new of Emu mail and understand its risks. Upjohn stuck dropped sharply after the i i is announcement closing to nday at $92.50. Some financial analysts speculated Tibai i lie spa criticism could be held against the drug in ii licensing decision. But Fra Deputy commissioner John Norris said the decision will be based on the scientific questions involved not on a press release. This is a Good company. It has Good management Norris told the associated press. On this occasion the went i Little beyond what was appropriate. Hut we will no in any sense give them anything other than a fair forum for reviewing the drug for safely and  and Upjohn has expressed Confidence hat the drug will be approved investing $25.7 million in a Kalamaras mich., manufacturing Plant. The drug also will be produced in Belgium and puerto Rico the company said. But the Fra s letter sharply rebuked the company and opened the question of whether minoxidil really does grow hair without undue risk. The company in the disputed press release said clinical trials at 27 medical centers Overall showed significant hair growth in a substantial proportion of balding men  those applying a 2 percent solution of minoxidil apparently the optimal dose 40 percent reported mod Erate hair growth White 8 percent described their hair growth As dense the company  65 percent of those receiving the 2 percent Solu Tion the company said the sire of the patient s Bald spot decreased. There was no change in 2fl percent of the patients and the diameter increased for 15 per cent Upjohn said no major Side effects attributable to thu drug were selected in the 17-Ccnicr study the company said. The Only apparent Side effects were common ski problems it said such As itching and staling. There have been 10 deaths among people who used either Amori cd or Bootleg solutions of Man Vidil. He in Many said but none appeared linked to the drug. The glowing Upjohn report sent its Slock snaring after it was released april 21.bill William Purvis of the Fra s drug advertising and Ibeling division said in the May 15 letter thai hil1press release falsely portrays minoxidil As an innocuous to run ii is our position thai minoxidil is i potent drug for which the full safely and in icily issues for chronic topical use have nol cd been t ugly evaluated or  open questions include ilu1 possible Side effect from using the drug Over Long periods Purvis said. Ever when in grows hair minoxidil must be used permanently or baldness returns. But the drug studies cited by the company lasted Only a year. Purvis also said the risk of possible Ink Rac Lions be tween minoxidil and Oiler Long term drills such As blood pressure pills has not been determined. That could be a Factor because even in a 2 Pel cent solution rubbed on the skin at least some minoxidil Dois make its Way into the bloodstream. One major newspaper Usa today called minoxidil a cure for baldness a description Purvis said flatly was a false conclusion we feel was encouraged by the tone of this press  Upjohn responded that in believed the press release was neither false nor  but it agreed to Stop further distribution of tie release. 1.1 million entries at your fingertips the Nippon Telegraph did Telephone corp. Not has developed a Telephone directory system Tor use with a personal computer in which Sorar 1.1 million entries of the four volume yellow pages for Tokyo Are recorded on one compact disk cd. Not which developed the system in cooperation with Sony corp. And Dai Nippon printing co plans to put the video cd directory on Sale in Tokyo next year. Price will depend upon demand. Pop Andreou offers cooperation against terrorism n to try a t m i it up i Andreas Papandreou has offered to to operate Wilh the United states and other Western countries in the struggle against terrorism the pro government weekly to Vima said sunday. Papandreou made the offer in a letter., to Secretary of state " " planning Greece inc week " a Hemment authorities were not inane no on the report. Papandreou spouse to a letter by the secret deplored the prime Mil on i in  Ali a Are Etc condemned the april 15 . Air strikes against Libya and has refused Loim pose sanctions against Moa mar Gad a by s regime for its alleged involvement in terrorism. During the parliamentary debate Papandreou Drew a of president Hafez Assad also accused of supporting Ter. Papandreou called for a  conference to define terrorism. To Vima said Papandreou wrote to Shultz that he condemns terrorist a Knuth the they Are trying to liberate particularly when they cause innocent casualties among third country nationals. Prime minister rejected Sug drafted of countries which aliegt9tltpfcil isl in terror ism the weekly said