European Stars And Stripes (Newspaper) - March 25, 1987, Darmstadt, Hesse Wednesday March 25, 1937 the stars and stripes Page 3 effects of aids drug stir controversy new York uh1 the drug at has offered the first Ray 0f Hope for prolonging the lives of aids patients but the severity of its Side effects appears to be worse than , some doctors say. As Many As half the patients taking at the first aids drug approved for prescription Sale May suffer Adverse effects thai could Force Almajo discontinue treatment or undergo blood transfusion cry 10 Daylo every month doctors say. To rep. Ted Weiss d-n.y., said saturday and drug administration should not have Ai the drug for marketing last week without knowing More about who it helps and who it harms Weiss Taid he expects to hold hearings on whether the Fra May be using aids to further its Agenda for deregulation of drugs before their effectiveness is proven. He also questioned unaudited statement about the Cost of Alfs development and said free distribution of at for research and compassionate use should have been continued until the drug is better understood. Fra approval loosens restrictions on the drug s distribution allowing the manufacturer Burroughs Well come to begin charging each patient up to $ 10,000 for a year s Supply. Wall Street analysts have projected that a to double Burroughs Willcome s total revenues. End of the 1990s. The Fra based its approval of the Dron studies in which 34 percent of paid ends Taki rat had to reduce dosages and get blood trans fusions or discontinue treatment said Kathy a a Jiff spokeswoman for Burroughs wellcome co. Of . But those reports War based on the first six months or clinical trials win the antiviral drug begun last february on 28 patients. Burroughs wellcome and the National cancer ans dilute. Which sponsored the How at works Tom it old a curl Hutu ditotto z in m vim on met tar Man Mot m a it u 0a. A an few 11 of tit trials have not released new data since september. In the preliminary studies at clinics around the United slates a statistically significant number of patients who suffered an aids related pneumonia were kept alive longer with at or than those who received no treatment. Scientists emphasize thai at docs not cure aids. But the drug can cause headaches nausea and most troublesome suppress Bone marrow production of White and red blood cells. Or. Arthur englard of St. Luke a Rosc Volt medical Center in new York said about 50 percent of his a ii ends were forced off the drug or required frequent blood transfusions. Some have required transfusions and a half to a month said englard 14 of an original 25 patients Slif some have effects at All said Chr physician whoop Otthat in Spile of possible prob lems his Prohas stoned at treatment with 23 Here is no other drug to Pul them on he said. At san Francisco general Hospital healthier arc and aids patients arc tolerating at better bul half of those in the primary clinical trial from last Spring had to drop out said the unit s protocol administrator. About one fourth arc doing Fine and another fourth arc touching it out said the administrator who declined to be identified. Transfusion needs with at have been so pronounced that the Irwin memorial blood Bank which supplies the City of san Francisco and surrounding counties projects a 5 percent increase in demand for blood this year said spokeswoman Sylvia Ramirez. Or. Samuel Brodur who led the National cancer time team that studied the drug acknowledges hat Myn Ains unknown bul he defended at As the he cited task survival Rales improved weight blood and Neuroh Hucal functions and lower Levels of aids viral protein so Popleon the drug even if everyone Saint flaw benefits there is no question some get the survival with at he said. But both Brodur and Burroughs we Hunt refused comment on whether fewer Palienie arc a Mif a the drug than expected saying they Are awaiting lion of further Dala. British social services Secretary nor Man Fowler right Speaks to aids experts attending a conference in Lon Don monday. With fouler is prof. Francis o Crady the conference s world a null org Bizalion i tills Alana with Genyn Swiss am ricin and British experts will try to determine trends the aids epidemic i Bruin will Lake. Advised to reverse decision on c-5b Peri Washington a the air Force could save by reversing a decision that pre Vernshe use of spare parts built for the original Oisa cargo plane in the newest Model of the a sport the c 5b, a Pentagon audit says. The audit performed by the Penta gon s Independent inspector Purat concluded the air Force changed its m ing procedures for c-5b spare parts la. April due loan apparent misguided con Cern Over maintenance procedures " the new plane officials at the service s air Jcj pics Center in san Antonio Texas prided that in most cases the pro Jeffa reliability of c-5b items was Bej Jothan Cor responding c-5a Iteni Jand hence spare pans for the two a pcs should not be mixed the audit Staj the idea was ups void using older spare parts that of flight undercut the de sign in the new c-5b, the auditors said Nde the decision 258 of 259 cd Al re parts that originally were Consi Dond interchangeable were banned for Eon the newer plane. Detailed review of 18 Sample items the auditors showed however that "13 c-5a items had no jul St clarity and reliability to supp Jmc c-5b air Craft without signified Arloss of pc for Mance or degradapr6f the of those Itari sampled. The auditors estimated a put $6.8 million of procurements Jatun be avoided by classifying the cup lems As two Way interchangeable Jupt Lac correspond ing c-5b Ising statistical projections we Coli i cd that $23.3 million of procurements " 180 of the 259 cab parts could to avoid by taking these e matters worse the auditors added Crich cd corp. The plane s prime contrib dior never changed its own internal of the spare pans As . It concluded thai of the relevant cab spare by repair parts should be stopped assessment is according to an the re port the air Force has a letter accepting the thrust of the a the service has refused to Slop air chases of new c-5b parts but has agreed to scale Back its orders until a technical evaluation is made of each Romance did t fizzle out in War Between the Colas Northampton mass. Api a Seille Mem has been reached in a damage suit filed by a former coca cola bottling company worker who claimed she was fired after falling in love with a Pepsi employee. Attorneys for both sides declined com ment monday on the details of the agreement except to say the settlement was satisfactory to All Amanda Cronin 3d, of Northampton who was then Amanda Blake sought 5600,000 damages from the coca cola bottling co. Of Northampton in 1985. She claimed in her Hampshire Superior court suit that the company told her she either had to break off her engagement 10 David Cronin who had left Coke to work for Pepsi persuade him to quit his Job with the competitor or quit herself. She contended she was fired when she declined to either give up her future Hus band or the Job she had held for eight years. Her attorney. Mark Mon. Said she now works in the data processing depart ment of mount Holyoke College
