European Stars and Stripes (Newspaper) - May 8, 1990, Darmstadt, Hesse                                Why dieters regain weight by Gina Kolata new York times a change in body enzymes May be one reason that Many people who lose weight quickly regain it. Researchers have found that when obese people lost weight they started overproducing an enzyme that makes it easier to get fat again. The enzyme helps plump up fat cells that were deflated by dieting allowing fat to be stored once again in body tissues. The effect of these High enzyme Levels is to make weight gain far easier for the formerly obese than it is for people who were never fat the researchers say. And the fatter the person was to begin with the More of the fat regaining enzyme they produced once when they were thin. The study of nine extremely obese people by or. Philp Kern of Cedars Sinai medical Center in los Angeles and his colleagues was published recently in the new England journal of Medicine. Quot i think it s exciting a said or. John d. Brunzell a professor of Medicine at the University of Washington in Seattle who has also studied the fat depositing enzyme. Brunzell said he was particularly intrigued by the possibility of understanding Why the enzyme Levels go up in formerly obese people. It could eventually be possible to a a figure out How to Block the brain from telling fat cells to increase their enzyme activity a he said. Quot studies like this will Chip away at the mentality that All people handle calories the same Way and that everybody can get to their Ideal weight if Only they try hard enough Quot said or. Kelly Brownell who is a director of the obesity research clinic at the University of Pennsylvania school of Medicine. Quot people who lose weight All say that it is harder to keep it off than to lose it in the first place Quot said Kern. He added that the new results Quot suggest a biological mechanism Quot for this common experience. In his study Kern followed the nine very obese people who dieted lost an average of about 90 pounds and kept the weight off for three months. The researchers measured Levels of the fat depositing enzyme Lipoprotein lipase before the people started their diets and after they had been at their new Low weights for three months. They found not Only that the enzyme Levels were consistently higher when the people were thin than when they were fat but also that the fatter the people were to Start with the higher their Lipoprotein lipase Levels were after they had reduced. It was As though the More weight a person had lost the More the body fought to regain the weight. In addition the investigators found the enzyme Levels increased because a Gene inside fat cells was activated indicating there May be a genetic switch that is flipped on to induce formerly obese people to put on fat again. Although the patients in this study were All very heavy some experts said they expected the findings to be More generally  vacations associated press weight watchers Magazine which devotes its upcoming july Issue to travel provides some advice for keeping the fat out of your vacation while leaving the fun in. Plan ahead. Request special meals while buying plane tickets for example. A with regular air plane food scrape the sauce off the entree have one or two bites and eat the bread. Done to pour dressing on the salad but dip the Fork into the dressing then eat some salad. For Long flights take snacks from Home like fresh fruit or vegetables sealed in plastic bags and stay out of the Airport snack shops if your flight is delayed. A choose one realistic goal for the trip like splitting desserts. A for car travel pack a Small cooler with diet sodas iced Tea bottled water individual Cereal boxes Yogurt fruits and vegetables. For Cruncher snacks bring Popcorn. 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