European Stars and Stripes (Newspaper) - April 02, 1991, Darmstadt, Hesse Early morning hazards to by Daniel q. Haney associated press. Ere s Seething to think about As you a climb out of bed in the morning a a. For the. Next two hours your risk of a dropping dead from a heart attack is twice As High As it is the rest of the Day a a a a a. _ ���-."7 you could of course stay in bed but sooner or a later you la have to get up for something. And that when the trouble starts. 7-,. Starting the Day is risky business. Besides heart attacks strokes also Are More common then and even painless temporary oxygen starvation of the. Heart a common condition known As ischaemia. A a a a blame nature for its strategy of giving the body a. Kickstart in the morning. Experts believe the hazards to the heart almost certainly result from the eruption of internal chemical and mechanical changes that break Loose the moment your feet hit the floor. It a. As unsettling As All of this May seem the discovery a of the perils of arising has been a genuine Delight to heart specialists. It May help answer one of the most v stubborn puzzles of their profession what exactly. Triggers a heart attack. A 7.7 1-7. A a 77 7 a a v searching for the underlying cause of the morning spate of heart attacks has become a hot area of medical study 5.0 research group around the United states what makes the scientists. A so Happy is the recognition of a pattern. Until recently it seemed heart attacks occurred erratically., throughout the Day no matter what people did.77 a this shows that heart attack is not a random. Phenomenon Quot said or. Richard Lee of Brigham and a. Women a Hospital in Boston Quot any time that we see something is not random it Means there May be a -. Way to intervene and prevent the . 7. Researchers Hope that if they know Pew stresses on. The heart increase in the morning they will be Well on v to zeroing in on the. Forces that touch off. Heart attacks and that will help them design new ways to prevent them. A Quot what is it in those first hours that triggers the heart a attack Quot asks or. James Muller of new England 7 Vvs a. Deaconess Hospital in Boston. Quot if we could figure it out we think it would apply to other times of the Day 1 As \ --7 a a a 7.,. 77 Muller pioneered the Field in 1985 with his Chance discovery that patients participating in a Large heart attack study were stricken More often in the morning hours. Since theol he and other researchers have focused especially on two questions what causes. A heart attacks then and what makes the heart More vulnerable to these stresses a 77.7 7 77. Most heart attacks begin when Lump of 7 cholesterol on the Wall of an artery a cracks open. A blood clot feb rms and Sticks to the break. This Lump. A. Bulges out into the artery choking off the flow of blood to the heart and a Section of heart muscle Dies -. _ the body a built in preparations to help its owner. Face the Rigours of the Day seem to increase the Odds of a heart attack in several ways. Perhaps the most important is a waking release of stress hormones. Such As Adrena in just standing up makes these. Hormones surge and the mental anxiety of getting the kids off to school fighting traffic and worrying about the problems that await at work makes the body pump out even More of them. A these hormones prod the heart to beat 1faster, the blood pressure to Rise arteries to narrow a experts believe these sudden. Changes put physical. Stress on plaques and increase the Odds that some of it them will crack and break a a and when that break occurs chances also Are greater in the morning that the body Wilt respond with -a.big, dangerous blood clot. 7 -7 blood cells called platelets1 that oversee clotting Are stickier in the morning and at the same time the it. Body a daily production of clot dissolving chemicals is at a Low ebb. 77 .v77.7&Quot-777 a. 7 7-�?T.7 7 7 Quot plaques very possibly rupture More commonly in the. Morning and they Are rupturing at a time when blood is More Closable Quot Lee said., a a a a -1 Lee working with engineers Alan Grodzinsky and Roger Kamm of the Massachusetts Institute is testing plaques removed from hearts. 7 during autopsies to see what kinds of stresses make them break. Quo this is one of several lines of study intended to learn what Quot makes some plaques vulnerable to rupture White others Are stable and How this susceptibility. Changes Over time. 7 -"7 -. 7 7 7. 7 77.7. 7. 7 7 researchers believe however that no single. A a morning triggers particularly important by itself. A a a a instead trouble starts when several of these built in. Stresses kick in same time perhaps along with some outward Burden such argument climbing a flight of stairs or smoking a cigarette 7, a a a a the concept is evolving that a heart attack is like. An air plane Accident Quot said Quot there Are a lot of flights where the Pilot misses the Landing,.or it s a bad foggy night and nothing terrible happens. But if you / Are Low on Luel and it s foggy and you miss a Landing and there Are two planes close together you May get an Adverse event a a7 7 7 the research already helps explain How medicines called Beta blockers which Blunt the effect of stress hormones can save lives studies show that the drugs reduce the morning Peak in heart attacks some doctors now recommend that people on Beta blockers take pills so the Medicine already Wilt be 7. A working when they awaken. A by identifying each heart attack trigger and understanding How it aggravates vulnerable plaques doctors believe they also can come up with Newa strategies to prevent heart attacks before they occur a a or. Peter Slone of Brigham and. Women a Hospital. A notes that until now has focused on saving the heart once a heart attack occurs. A there is now a new dimension of research going one step Back in time to figure out Why who plaque _ ruptures in the first place Quot he said. A ii that can be prevented there will be major benefits for How men and women differ in the course of heart disease women get heart disease later than men As a general Rule but it is usually More severe m. Women than in men. A heart disease is the leading cause of death in women after the 66 in men it is the no. 1 killer from the age of 39. Though few women have heart attacks before menopause the protective effect of Lemale sex hormones has not been firmly established by researchers a differences at each Stag of disease predicting trouble although women and men Are at risk for heart disease if their cholesterol is High studies thus far have shown that Only m. Women do of. Plaque causing triv. Glycerides Potto particular Skaven in the a. Sence of High cholesterol. I Aque Lea d s. T of. A upper vessel blockage. First sign women often have Chest pains for a Long time before a heart attack in men. Such pains. More often mean a 7 heart attack has a 7 ready begun. Survival after an a attack women Are twice As Likely As men to die. Within 60 Days. In a six month study 27 percent a of women and 15 percent of men died. Ihfe clogged vessel a survival of bypass surgery women do Only half As Welt As men. In one study 2,9.percent.-of. The women and 1 <3 percent of the men died at the time of surgery. Women s smaller hearts Are harder to operate on. But other factors a re suspected to be at work suggestive Early findings studies in monkeys indicate that the hearts and blood vessels of both sexes have receptors but that the mate hearts have. More receptors for testosterone and hormones released under stress. In rats female blood vessels Are More elastic. Bypass not
